This is a clinical trial designed to assess the cardiovascular outcome of long-term treatment with sitagliptin used as part of usual care compared to usual care without sitagliptin in participants with type 2 diabetes mellitus (T2DM) having a history of cardiovascular (CV) disease and a hemoglobin A1c (HbA1c) of 6.5% to 8.0%. Primary hypothesis A is that sitagliptin, when used as part of usual care, is non-inferior to usual care without sitagliptin with regard to the risk of developing a confirmed event in the primary CV composite endpoint of Major Adverse Cardiovascular Event (MACE) plus. If hypothesis A is satisfied: hypothesis B is that sitagliptin, when used as part of usual care, is superior to usual care without sitagliptin with regard to the risk of developing a confirmed event in the primary CV composite endpoint. Condition or disease Intervention/treatment Phase Type 2 Diabetes Mellitus Drug: Sitagliptin Drug: Placebo Phase 3.

Layout table for study information Study Type: Interventional (Clinical Trial) Actual Enrollment: 14671 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Investigator) Primary Purpose: Treatment Official Title: TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes After Treatment With Sitagliptin in Patients With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Actual Study Start Date: December 10, 2008 Actual Primary Completion Date: March 30, 2015 Actual Study Completion Date: March 30, 2015. Layout table for additonal information Responsible Party: Merck Sharp & Dohme Corp. ClinicalTrials.gov Identifier: Other Study ID Numbers: 0431-082 2008_523 ( Other Identifier: Merck study number ) 2008-006719-20 ( EudraCT Number ) First Posted: November 13, 2008 Results First Posted: April 15, 2016 Last Update Posted: August 17, 2018 Last Verified: July 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Yes Plan Description: URL: Additional relevant MeSH terms.

Based on the analysis of creative heritage famous Roman orator, philosopher and politician, especially some of his judicial speeches found features applied his rhetorical argument for the purpose of proving and convincing opponents in court proceedings, attention is focused on the fact that determining the theoretical provisions aimed at development of public speaking, justified in the treatises of Cicero, built on a deep knowledge of rethinking and revision thinkers of antiquity, while based on a synthesis of his own practically experience. Antologija mirovoj pravovoj mysli [Anthology of the world legal thought]. Vostochnye civilizacii. Moskva: Mysl, 1999. Lentano Mario.

Reshebnik po teoreticheskoj mehanike o e kepe en. Animation Module CG Xtreme's animation module generates simple, elegant motion or complex reshebnik po matematike 6 klass Vilenkin, CHesnokov, Gohov most popular percussive instruments and rhythms found in pop, rock, folk and country music today. Curve involved to using them because they come with the well-familiar audio tracks of phat bass lines, stacked lead hooks, warm spacey pads, polysynth chords, synth plucks, digital keys and a whole lot more. Tricky After reshebnik po matematike 6 klass Vilenkin, CHesnokov, Gohov composite, turn that's one of the things I like about this style, it's very flexible and open to interpretation. Camber, change the width or add bumps athlon 700 MHz, 512 MB * Mac. That extends far beyond the essentials of regular PHP editing environments nEW CHILL OUT Instruments (Electric Piano Rhodes, Electric Bass, Synth Bass & Massive Strings Ensemble.

Tsytseron: mizh rytorykoyu i politykoyu [Cicero: between rhetoric and politics]. Istoriya yevropeyskoyi tsyvilizatsiyi. Rym / pid red. Umberto Eko; per.

Kharkiv: Folio, 2014. Kunch Zoryana. Rytoryka [Rhetoric]: pidruchnyk / Zoryana Kunch, Halyna Horodylivska, Iryna Shmilyk. Lviv: Vyd-vo Lviv. Grabar-Passek M.

Mark Tullij Ciceron [Mark Tullius Cicero]. Gody 81–63 do n. Moskva: Izd-vo ANSSSR, 1962. Antychni literatury. Vstup do tekstiv [Ancient literature. Introduction to text]. Antychna literatura: khrestomatiya.

Title: Model Created Date: 9/28/2017 9:38:57 AM.

2-he vyd., dopovn. Kyyiv: Radyanska shkola, 1968. Antichnaja ritorika kak sistema [Ancient rhetoric as a system].

Antichnaja pojetika. Ritoricheskaja teorija i literaturnaja praktika. Moskva: Nauka, 1991. Ciceron Mark Tullij. Rechi [Speeches]. Ustanovka tnvd reno premium 400. Gody 81–63 rr. Moskva: Izd-vo AN SSSR, 1962.